Powers and abilities
Effects on Kryptonians
Blue Kryptonite strips Kryptonians of all their powers, making them mortal and, thus, susceptible to damage and pain as with any human. In Smallville episodes, Blue Kryptonite is used against Clark Kent (aka Superman) and turns him mortal as long as he wears it as an object on his body, like a ring, a necklace, or a watch.
Effects on Bizarro
Blue Kryptonite magnifies Bizarro's powers to such an insane degree that it causes him to shake and explode.
Effects on humans
Blue Kryptonite can drastically improve the health of anything organic, such with water, crops, and humans. Continual consumption of Blue Kryptonite puts humans in a perfect state of health.
Blue Kryptonite can be counteracted with solid lead.