The following is a list of all the DC Comics characters adapted into Smallville:

1. Clark Kent (Pilot)
2. Lana Lang (Pilot)
3. Lex Luthor (Pilot)
4. Pete Ross (Pilot)
5. Martha Kent (Pilot)
6. Jonathan Kent (Pilot)
7. Captain Maggie Sawyer (Insurgence)
8. Jor-El (Calling)
9. Morgan Edge (Exile)
10. Dr. Teng (Phoenix)
11. Perry White (Perry)
12. Dr. Claire Foster (Perry)
13. Lara-El (Memoria)
14. Lois Lane (Crusade)
15. General Sam Lane (Gone)
16. Bart Allen (Run)
17. Mikhail Mxyzptlk (Jinx)
18. Shelby (Krypto)
19. Lucy Lane (Lucy)
20. Brainiac (Arrival)
21. Aethyr (Arrival)
22. Nam-Ek (Arrival)
23. Arthur Curry (Aqua)
24. Zod (Solitude)
25. Andrea Rojas (Vengeance)
26. Victor Stone (Cyborg)
27. Oliver Queen (Sneeze)
28. John Jones (Static)
29. Titan (Combat)
30. Bizarro (Phantom)
31. Kara Kent (Bizarro)
32. Zor-El (Lara)
33. Dinah Lance (Siren)
34. Bette Sans Souci (Plastique)
35. Maxima (Instinct)
36. Faora (Bloodline)
37. Doomsday (Bride)
38. Rokk Krinn (Legion)
39. Imra Ardeen (Legion)
40. Garth Ranzz (Legion)
41. Persuader (Legion)
42. Dan Turpin (Bulletproof)
43. Dr. Emil Hamilton (Bulletproof)
44. Winslow Schott (Requiem)
45. Zatanna Zatara (Hex)
46. Bruno Mannheim (Stiletto)
47. Leslie Willis (Injustice)
48. Rudy Jones (Injustice)
49. Neutron (Injustice)
50. James Bartholomew Olsen (Doomsday)
51. John Corben (Savior)
52. Victoria Sinclair (Roulette)
53. Mia Dearden (Crossfire)
54. Zan (Idol)
55. Jayna (Idol)
56. Carter Hall (Absolute Justice, Part 1)
57. Kent Nelson (Absolute Justice, Part 1)
58. Courtney Whitmore (Absolute Justice, Part 1)
59. Cameron Mahkent (Absolute Justice, Part 1)
60. Sylvester Pemberton (Absolute Justice, Part 1)
61. Joar Mahkent (Absolute Justice, Part 1)
62. Wesley Dodds (Absolute Justice, Part 1)
63. Al Pratt (Absolute Justice, Part 1)
64. Ted Grant (Absolute Justice, Part 1)
65. Jay Garrick (Absolute Justice, Part 1)
66. Alan Scott (Absolute Justice, Part 1)
67. Abigail Hunkel (Absolute Justice, Part 1)
68. Inza Nelson (Absolute Justice, Part 1)
69. Amanda Waller (Absolute Justice, Part 2)
70. Siobhan McDougal (Escape)
71. Maxwell Lord (Charade)
72. Franklin Stern (Charade)
73. Granny Goodness (Salvation)
74. Rick Flag (Lazarus)
75. Conner Kent (Lazarus)
76. Darkseid (Lazarus)
77. Cat Grant (Shield)
78. Deadshot (Shield)
79. Shayera Hall (Shield)
80. Gordon Godfrey (Shield)
81. Brainaic 5 (Homecoming)
82. Emil LaSalle (Ambush)
83. Desaad (Abandoned)
84. Harriet (Abandoned)
85. Lashina (Abandoned)
86. Ella Lane (Abandoned)
87. Mera (Patriot)
88. Slade Wilson (Patriot)
89. Clark Luthor (Luthor)
90. Amos Fortune (Fortune)
91. Booster Gold (Booster)
92. Jaime Reyes (Booster)
93. Ted Kord (Booster)
94. Ron Troupe (Booster)
95. Skeets (Booster)
96. Black Manta (Prophecy)
97. Captain Cold (Prophecy)
98. Solomon Grundy (Prophecy)